Primary Adenosquamous Carcinoma Of The Skin In The Occipital Region: A Case Report

Primary cutaneous adenosquamous carcinomas are very rare entities with only few published reports in literature. We describe a primary cutaneous adenosquamous carcinoma found in the occipital region of a 53 year old man with a pediculated tumor of 7 cm in diameter and an ulcerated, verrucous aspect with serous exudations. There was no clinical or radiologic evidence of invasion of the cranial vault or another primary tumor e.g. of the salivary glands. The histologic picture consisted of two different components: masses of cords of a squamous cell carcinoma and a second element with goblet cells in the center of the epidermid areas. Histochemical studies and immunohistochemistry demonstrated the presence of the two components described. The epidermis was dysplastic. The carcinoma was infiltrative with a multifocal origin from the basal layer of the epidermis.